Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Toll-like receptor 8 monoclonal antibody (44C143) (R-PE conjugate)

 
ALX-804-376R-C100 100 µg R-PE 511.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:TLR8, CD288
 
Clone:44C143
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to aa 750-850 of the cytoplasmic portion of human TLR8 (Toll-like receptor 8).
 
UniProt ID:Q9NR97
 
Species reactivity:Human, Mouse
 
Applications:Flow Cytometry
 
Recommended Dilutions/Conditions:Flow Cytometry (intracellular, 0.5-2µg per 106 cells; cell surface: see Xu et al. (2006) for details)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~120kDa by Western blot.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
 
Handling:Do not freeze. Protect from light.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Scientific Background:The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kDa.
 
Technical Info/Product Notes:Replacement for ADI-CSA-825
 
Toll-like receptor 8 monoclonal antibody (44C143) (R-PE conjugate) FACS
Figure: Flow analysis of TLR8 in Ramos cells using 2μg of MAb to Toll-like Receptor 8 (44C143) (Prod. No. ALX-804-376R). Shaded histogram represents Ramos cells without antibody; green represents isotype control; red represents MAb to Toll-like Receptor 8 (44C143)."
Please mouse over
Toll-like receptor 8 monoclonal antibody (44C143) (R-PE conjugate) FACS

Product Literature References

High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production: S. Xu, et al.; Surgery 140, 170 (2006), Abstract;

Related Products

Toll-like receptor 8 monoclonal antibody (44C143) 

Flow Cytometry, IHC (PS), WB | Print as PDF
 
ALX-804-376-C100 100 µg 392.00 USD
Do you need bulk/larger quantities?
 

Toll-like receptor 8 monoclonal antibody (44C143) (biotin conjugate) 

ELISA | Print as PDF
 
ALX-804-376B-C100 100 µg Biotin 409.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
TLR
TLR8
By biological activity:
TLR Monoclonal antibody
TLR8 Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2019 Enzo Life Sciences, Inc.,