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Bcl-w monoclonal antibody (16H12)

 
ALX-804-354-C100 100 µg 356.00 USD
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Product Specification

Alternative Name:BCL2L2
 
Clone:16H12
 
Host:Rat
 
Isotype:IgG2a
 
Immunogen:Recombinant human Bcl-w.
 
UniProt ID:Q92843
 
Species reactivity:Human, Mouse, Rat
Dog, Monkey
 
Applications:IP, WB
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 25% glycerol and 0.02% sodium azide.
 
Use/Stability:Stable for up to 3 months when stored at +4°C.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Western Blot works for transfected and Bcl-w overproducing cells. For detection of endogenous Bcl-w, immunoprecipitation is required.
 
804-354-n
Figure: Western blot showing the detection of Bcl-w in fractionated lysates of mouse tissues with clone 16H12. Antibody specificity is indicated by the absence of the expected 21 kDa protein in Bcl-w -/- testis control tissues. The 67 kDa band is Hsp-70 used as an equal loading control.
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804-354-n

Product Literature References

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis: G. Cao, et al.; J. Neurosci. 22, 5423 (2002), Abstract;
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w: L.A. O'Reilly, et al.; Cell Death Differ. 8, 486 (2001), Abstract;
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine: D.M. Pritchard, et al.; Oncogene 19, 3955 (2000), Abstract;

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