Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Cathepsin L/procathepsin L (human) monoclonal antibody (CLP 1/36)

 
ALX-804-292-C200 200 µg 399.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Clone:CLP 1/36
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to aa 200-217 (Y200SVANDTGFVDIPKQEKA217) of human procathepsin L.
 
UniProt ID:P07711 (cathepsin L1), O60911 (cathepsin L2)
 
Species reactivity:Human
 
Specificity:Recognizes the epitope I211PKQ214 of human procathepsin L. Recognizes mature human single or two chain cathepsin L (heavy chain) and human procathepsin L.
 
Crossreactivity:Does not cross react with mature cathepsins B, D, H, K, S and procathepsins B, D, F, S, W.
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (paraffin sections after microwave treatment)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.01% thimerosal.
 
Handling:Do not freeze.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:+4°C
 
Scientific Background:Cathepsin L [EC 3.4.22.15] is a lysosomal endopeptidase belonging to the papain family of the closely related cysteine proteases superfamily. The enzyme is ubiquitously distributed in the lysosomes of all cells and seems to be involved in a variety of disorders in which the pathological destruction of the extracellular matrix is one of the main characteristics.
 
LBS-AB-CL-2004
Figure: Epitope map of mature cathepsin L.
Please mouse over
LBS-AB-CL-2004

Product Literature References

Immunohistochemical and clinical evaluation of cathepsin expression in soft tissue sarcomas: P. Wurl, et al.; Virchows Arch. 430, 221 (1997), Abstract;
Monoclonal antibodies against cathepsin L and procathepsin L of different species: E. Weber, et al.; Hybridoma 16, 159 (1997), Abstract;
Hybridoma cells producing antibodies to cathepsin L have greatly reduced potential for tumour growth: E. Weber, et al.; J. Cancer. Res. Clin. Oncol. 120, 564 (1994), Abstract;

Product Toolbox

PRODUCT RESOURCES

Print as PDF
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Cathepsin
By biological activity:
Cathepsin Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Brochures
Essential Research Tools for Neurodegeneration & Neural Signaling
Essential Research Tools for Neurodegeneration & Neural Signaling
Download as PDF

Technical Posters
Disease-Associated Stress Signaling
Disease-Associated Stress Signaling
Download as PDF

All new literature pieces

Recommend this page

 
Keep in touch

©2017 Enzo Life Sciences, Inc.,