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Granzyme B (human) monoclonal antibody (GrB7)

 
ALX-804-198-C050 50 µg 486.00 USD
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Product Specification

Clone:GrB7
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Human granzyme B.
 
UniProt ID:P10144
 
Species reactivity:Human
 
Crossreactivity:Does not cross-react with granzyme A.
 
Applications:IHC (PS), WB
 
Recommended Dilutions/Conditions:Immunohistochemistry (paraffin sections, 1:20)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~33kDa by Western blot.
Not recommended for IHC (FS).
 
Quantity:1ml is sufficient for >200 tests.
 
Formulation:Liquid. In serum free culture supernatant containing 1% BSA and 0.1% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 

Product Literature References

Analysis of major histocompatibility complex class I expression on Reed- Sternberg cells in relation to the cytotoxic T-cell response in Epstein- Barr virus-positive and -negative Hodgkin's disease: J.J. Oudejans, et al.; Blood 87, 3844 (1996), Abstract;
Granzyme B expression in Reed-Sternberg cells of Hodgkin's disease: J.J. Oudejans, et al.; Am. J. Pathol. 148, 233 (1996), Abstract;
Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood: J.A. Kummer, et al.; Clin. Exp. Immunol. 100, 164 (1995), Abstract;
Granzyme B-expressing peripheral T-cell lymphomas: neoplastic equivalents of activated cytotoxic T cells with preference for mucosa- associated lymphoid tissue localization: P.C. de Bruin, et al.; Blood 84, 3785 (1994), Abstract;
Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins: J.A. Kummer, et al.; J. Immunol. Meth. 163, 77 (1993), Abstract;

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