BCMA (human), mAb (Vicky-1) (PE conjugate)

Alternative Name:	B cell maturation protein, TNFRSF 17, CD269

Concentration:	1mg/ml

Purity Detail:	Protein G-affinity purified.

Formulation:	Liquid. In PBS containing 0.02% sodium azide.

Clone:	Vicky-1

Isotype:	Rat IgG1

Immunogen:	Recombinant human BCMA extracellular domain (aa 2-54) (Prod. No. ALX-522-026).

Specificity:	Recognizes human BCMA. Does not cross-react with mouse BCMA. Detects a band of ~40kDa by Western blot.

Application:	Flow Cytometry (1:100) Optimal conditions must be determined individually for each application.

Short Term Storage:	+4°C

Long Term Storage:	+4°C

Miscellaneous/General:	BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes and belongs structurally to the TNF receptor family. BCMA associates with BAFF, APRIL, TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-κB, Elk-1, c-Jun N-terminal kinase (JNK), and p38 mitogen-activated protein kinase. BCMA plays an important role in B cell development, function and regulation.