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BCMA (human) monoclonal antibody (Vicky-1) (biotin conjugate)

 
ALX-804-151B-C100 100 µg 410.00 USD
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Product Specification

Alternative Name:B cell maturation protein, TNFRSF 17, CD269
 
Clone:Vicky-1
 
Host:Rat
 
Isotype:IgG1
 
Immunogen:Recombinant human BCMA extracellular domain (aa 2-54) (Prod. No. ALX-522-026).
 
UniProt ID:Q02223
 
Species reactivity:Human
 
Crossreactivity:Does not cross-react with mouse BCMA.
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:ELISA (1:1,000)
Western Blot (1:1,000, colorimetric)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein G-affinity purified.
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Scientific Background:BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes and belongs structurally to the TNF receptor family. BCMA associates with BAFF, APRIL, TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-κB, Elk-1, c-Jun N-terminal kinase (JNK), and p38 mitogen-activated protein kinase. BCMA plays an important role in B cell development, function and regulation.
 
ALX-804-151B WB
Western Blot Analysis of BCMA: Lane 1: MWM, Lane 2: BCMA (human):Fc (human), (recombinant) (Prod. No. ALX-522-026)
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ALX-804-151B WB

General Literature References

TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase: A. Hatzoglou, et al.; J. Immunol. 165, 1322 (2000), Abstract;

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