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Troy (human) monoclonal antibody (Giu.Li)

 
ALX-804-146-C050 50 µg 345.00 USD
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Product Specification

Alternative Name:TAJ, TNFRSF 19
 
Clone:Giu.Li
 
Host:Rat
 
Isotype:IgG
 
Immunogen:Recombinant human Troy cysteine-rich domain (aa 1-168) (Prod. No. ALX-522-045).
 
UniProt ID:Q9NS68
 
Source:Purified from concentrated hybridoma tissue culture supernatant.
 
Species reactivity:Human
 
Applications:Flow Cytometry
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Use/Stability:Stable for at least 1 year after receipt when stored as recommended.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
804-146 new
Figure: HEK 293T cells were mock transfected (thin line) or transfected with an expression coding for the extracellular domain of human Troy (thick line).
Method: Cells (5x105) were incubated on ice for 30 min in 50µl FACS buffer (PBS, 5% Fetal calf serum, 0.02% azide) containing 1µg/ml of monoclonal antibody to Troy (Giu.Li). After washing in FACS buffer, R-PE-conjugated antibody to rat IgG (Prod. No. ALX-211-053) was added. Cells were incubated on ice for 30 min, washed and analyzed by flow cytometry.
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804-146 new

General Literature References

TRAF6-deficient mice display hypohidrotic ectodermal dysplasia: A. Naito, et al.; PNAS 99, 8766 (2002), Abstract; Full Text
TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death: M.T. Eby, et al.; J. Biol. Chem. 275, 15336 (2000), Abstract; Full Text
TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles: T. Kojima, et al.; J. Biol. Chem. 275, 20742 (2000), Abstract; Full Text

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Troy (human):Fc (human), (recombinant) 

Produced in HEK 293 cells. The cysteine-rich domain of human Troy (TAJ) (aa 1-168) is fused to the Fc portion of human IgG1., ≥90% (SDS-PAGE) | Print as PDF
 
ALX-522-045-C050 50 µg 382.00 USD
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