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BAFF (human), mAb (Buffy-1) (FITC conjugate)

 
ALX-804-128F-T100 100 tests FITC 369.00 USD
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Product Specification

Alternative Name:zTNF4, THANK, BLyS, TALL-1, TNFSF 13B/20, CD257
 
Concentration:1mg/ml
 
Purity:≥95% (SDS-PAGE)
 
Formulation:Liquid. In PBS containing 0.02% sodium azide.
 
Clone:Buffy-1
 
Isotype:Rat IgG2a
 
Immunogen:Recombinant human soluble BAFF (aa 83-285) (Prod. No. ALX-522-025).
 
Specificity:Recognizes membrane-bound human BAFF. Detects endogenous protein by FC.
 
Application:Flow Cytometry
Immunocytochemistry
 
Short Term Storage:+4°C
 
Long Term Storage:+4°C
 
Use/Stability:Stable for at least 6 months after receipt when stored as recommended.
 
Handling:Do not freeze. Protect from light.
 
Background / Technical Information:1 test means: 1µl of a 0.1mg/ml stock solution were used to stain 200’000 cells in a sample volume of 50µl.
 
804-128
Schematic structure of human soluble BAFF (rec.) (aa 83-285). Recognizes the stalk region present in the membrane-bound form of hBAFF.
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804-128

Product Literature References

BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone: J. Moreaux, et al.; Blood 103, 3148 (2004), Abstract;
Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival: A.J. Novak, et al.; Blood 100, 2973 (2002), Abstract; Full Text
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth: P. Rennert, et al.; J. Exp. Med. 192, 1677 (2000), Abstract;
BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000), Abstract; Full Text
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999), Abstract;

General Literature References

BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population: J.S. Thompson, et al.; J. Exp. Med. 192, 129 (2000), Abstract;
BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth: P. Schneider, et al.; J. Exp. Med. 189, 1747 (1999), Abstract;
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