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HSP60 (bacterial) monoclonal antibody (A57-B9)

ALX-804-072-R100 100 µl 624.00 USD
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Product Specification

Alternative Name:Heat shock protein 60 (bacterial)
Immunogen:Recombinant Chlamydia trachomatis HSP60 (heat shock protein 60).
UniProt ID:P0C0Z7
Species reactivity:Chlamydia
Specificity:Recognizes all three genera of Chlamydia HSP60. Epitope mapping studies suggest binding of aa 517-522.
Crossreactivity:Minimally cross-reacts with Borrelia burgdorfi HSP60. Does not cross-react with E. coli GroEL or human HSP60.
Applications:ICC, IP, WB
Recommended Dilutions/Conditions:Immunocytochemistry (1:500)
Western Blot (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~60kDa by Western blot.
Formulation:Liquid. Ascites diluted in PBS containing 0.05% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C

Product Literature References

Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact: C. Waguia Kontchou, et al.; Cell. Microbiol. 18, 1583 (2016), Abstract;
Monoclonal antibodies define genus-specific, species-specific and cross-reactive epitopes of the chlamydial 60-kilodalton heat shock protein (hsp60): Specific immunodetection and purification of chlam: Y. Yuang, et al.; Infect. Immun. 60, 2288 (1992), Abstract;

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