Purinergic receptor P2X7 (mouse), mAb (HANO43)



ALX-802-027-L001	1 ml	371.00 USD

Product Specification

Alternative Name:	P2X purinoceptor 7, P2RX7

Formulation:	Liquid. Hybridoma supernatant containing 0.02% sodium azide.

Clone:	HANO43

Isotype:	Rat IgG2b

Immunogen:	Vector containing the cDNA of mouse purinergic receptor P2X7.

Specificity:	Recognizes mouse purinergic receptor P2X7.

Application:	Flow Cytometry (1:1-1:10) Immunocytochemistry (1:1-1:10) Immunoprecipitation (1:1-1:10)

Long Term Storage:	+4°C

Positive Control:	HEK cells transfected with an expression plasmid for mouse purinergic receptor P2X7 can be used as positive control.

Product Literature References

Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice: Y.G. Chen, et al.; J. Immunol. 186, 4278 (2011), Abstract;

Murine epidermal Langerhans cells and keratinocytes express functional P2X7 receptors: J.N. Tran, et al.; Exp. Dermatol. 19, e151 (2010), Abstract; Full Text

ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site: S. Adriouch, et al.; FASEB J. 22, 861 (2007), Abstract; Full Text

Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation: S. Möller, et al.; Purinergic Signal. 3, 359 (2007), Abstract; Full Text

P2X7 receptor expression levels determine lethal effects of a purine based danger signal in T lymphocytes: F. Aswad & G. Dennert; Cell. Immunol. 243, 58 (2006), Abstract;

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization: S. Adriouch, et al.; Cell. Immunol. 236, 72 (2005), Abstract;