Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

MVP/LRP (human) monoclonal antibody (LRP-56)

 
ALX-801-005-C050 50 µg 410.00 USD
 
ALX-801-005-C100 100 µg 701.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:Major vault protein/Lung resistance protein
 
Clone:LRP-56
 
Host:Mouse
 
Isotype:IgG2b
 
Immunogen:Human MVP/LRP (major vault protein/lung resistance protein).
 
UniProt ID:Q14764
 
Species reactivity:Human
 
Specificity:Recognizes an internal epitope (P110) of human MVP/LRP, which is overexpressed in various human non-P-glycoprotein MDR tumor cell lines.
 
Applications:Flow Cytometry, ICC, IHC (FS), IHC (PS)
 
Recommended Dilutions/Conditions:Recommended starting dilution is 1:20. Suggested dilutions/conditions may not be available for all applications. Optimal should be determined individually for each application.
 
Application Notes:Flow Cytometry: cell permeabilization required)
Immunocytochemistry: cytospin preparations
 
Positive Control:Cell lines: Appropriate drug-sensitive parental cell lines and their multdrug resistant derivatives prepared by the same methods as the test specimens should be used as control materials.
Tissue: Human colon, kidney, bronchus or adrenal are recommended.
 
Formulation:Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
801-005
Figure: Liver cells stained with LRP-56 (ALX-801-005).
Please mouse over
801-005

Product Literature References

The formation of vault-tubes: a dynamic interaction between vaults and vault PARP: A. Van Zon, et al.; J. Cell Sci. 116, 4391 (2003), Abstract;
Detection of the Mr 110,000 lung resistance-related protein LRP/MVP with monoclonal antibodies: A.B. Schroeijers, et al.; J. Histochem. Cytochem. 49, 1379 (2001), Abstract;
Immunohistochemical analysis of drug resistance-associated proteins in ovarian carcinomas: D. Mayr, et al.; Pathol. Res. Pract. 196, 469 (2000), Abstract;
The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines: A.B. Schroeijers, et al.; Cancer Res. 60, 1104 (2000), Abstract; Full Text
Immunohistochemical detection of the human major vault protein LRP with two monoclonal antibodies in formalin-fixed, paraffin-embedded tissues: A.B. Schroeijers, et al.; Am. J. Pathol. 152, 373 (1998), Abstract;
Identification of novel drug resistance-associated proteins by a panel of rat monoclonal antibodies: M.J. Flens, et al.; Int. J. Cancer 73, 249 (1997), Abstract;
Membrane transport proteins associated with drug resistance expressed in human melanoma: D. Schadendorf, et al.; Am. J. Pathol. 147, 1545 (1995), Abstract;
Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance: R.J. Scheper, et al.; Cancer Res. 53, 1475 (1993), Abstract;

Product Toolbox

PRODUCT RESOURCES

Print as PDF
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
Major vault protein
By biological activity:
Major vault protein Monoclonal antibody
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Product Flyers
Detect Activity of Major ABC Transporter Proteins
Detect Activity of Major ABC Transporter Proteins
Download as PDF

All new literature pieces

Recommend this page

 
Keep in touch

©2017 Enzo Life Sciences, Inc.,