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Territrem B

Acetylcholine esterase inhibitor
 
ALX-630-117-MC05 0.5 mg 156.00 USD
 
ALX-630-117-M001 1 mg 295.00 USD
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Tremorgenic mycotoxin. Potent and specific, noncovalent yet irreversible inhibitor of acetylcholinesterase (IC50=8nM).

Product Specification

Formula:C29H34O9
 
MW:526.6
 
Source:Isolated from Aspergillus terreus.
 
CAS:70407-20-4
 
RTECS:QL6284000
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in methanol; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
630-117
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630-117

Product Literature References

Territrems B and C metabolism in human liver microsomes: major role of CYP3A4 and CYP3A5: F.C. Peng, et al.; Toxicology 218, 172 (2006), Abstract;
Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism: J.W. Chen, et al.; J. Biol. Chem. 274, 34916 (1999), Abstract; Full Text
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity: F. Kuno, et al.; J. Antibiot. 49, 742 (1996), Abstract;
Territrems: Naturally Occurring Specific Irreversible Inhibitors of Acetylcholinesterase: J.W. Chen & K.H. Ling; J. Biomed. Sci. 3, 54 (1996), Abstract;
Effects of territrem-B on cholinergic responses of snail neuron: V.L. Arvanov, et al.; Neurosci. Lett. 152, 69 (1993), Abstract;
Biosynthesis of Territrems by Aspergillus terreus: K.H Ling & Y.W. Peng; Appl. Environ. Microbiol. 54, 585 (1988), Abstract; Full Text
Territrems, tremorgenic mycotoxins of Aspergillus terreus: K.H. Ling, et al.; Appl. Environ. Microbiol. 37, 355 (1979), Abstract; Full Text

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