Trichothecene group mycotoxin. Induces apoptosis
Product Details
| Alternative Name: | 15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene |
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| Formula: | C22H32O8 |
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| MW: | 424.5 |
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| Source: | Semisynthetic, derived from T2 toxin from Fusarium tricinctum. |
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| CAS: | 26934-87-2 |
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| RTECS: | YD0050000 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White to slight yellow solid. |
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| Solubility: | Soluble in 100% ethanol, DMSO or ethyl acetate. Slightly soluble in petroleum ether; poorly soluble in water. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res.
54, 87 (2015),
Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis,
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A practical method for measuring deoxynivalenol, nivalenol, and T-2 + HT-2 toxin in foods by an enzyme-linked immunosorbent assay using monoclonal antibodies: T. Yoshizawa, et al.; Biosci. Biotechnol. Biochem.
68, 2076 (2004),
Abstract;
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Mechanisms involved in the induction of apoptosis by T-2 and HT-2 toxins in HL-60 human promyelocytic leukemia cells: J.A. Holme, et al.; Cell Biol. Toxicol.
19, 53 (2003),
Abstract;
Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice: Z. Islam, et al.; Biosci. Biotechnol. Biochem.
62, 1492 (1998),
Abstract;
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