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Thaxtomin A

Phytotoxin
 
ALX-630-109-M001 1 mg 338.00 USD
 
ALX-630-109-M005 5 mg 1,035.00 USD
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Phytotoxin. Causes plant cell necrosis at nanomolar concentrations. Demonstrated to be produced by bacterial nitric oxide synthases (NOS).

Product Specification

Alternative Name:Thaztomin A
 
Formula:C22H22N4O6
 
MW:438.4
 
Source:Isolated from Streptomyces bottropensis.
 
CAS:122380-18-1
 
Purity:≥98% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Yellow powder.
 
Solubility:Soluble in DMSO or dimethyl formamide; partially soluble in methanol or 100% ethanol;
 
Shipping:Shipped on Blue Ice
 
Short Term Storage:+4°C
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 1 year after receipt when stored at -20°C.
 
Handling:After reconstitution protect from light at -20°C.
 
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Product Literature References

Thaxtomin A induces programmed cell death in Arabidopsis thaliana suspension-cultured cells: I. Duval, et al.; Planta 222, 820 (2005), Abstract;
Nitration of a peptide phytotoxin by bacterial nitric oxide synthase: J.A. Kers, et al.; Nature 429, 79 (2004), Abstract;
An Arabidopsis mutant resistant to thaxtomin A, a cellulose synthesis inhibitor from Streptomyces species: W.R. Scheible, et al.; Plant Cell 15, 1781 (2003), Abstract; Full Text
More chemistry of the thaxtomin phytotoxins: R.R. King, et al.; Phytochemistry 64, 1091 (2003), Abstract;
Involvement of a cytochrome P450 monooxygenase in thaxtomin A biosynthesis by Streptomyces acidiscabies: F.G. Healy, et al.; J. Bacteriol. 184, 2019 (2002), Abstract; Full Text
Selection and characterization of microorganisms utilizing thaxtomin A, a phytotoxin produced by streptomyces scabies: C.L. Doumbou, et al.; Appl. Environ. Microbiol. 64, 4313 (1998), Abstract; Full Text

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