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T-2 Toxin

Monoamine oxidase inhibitor
 
ALX-630-101-M001 1 mg 45.00 USD
 
ALX-630-101-M005 5 mg 164.00 USD
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Mycotoxin. Induces DNA damage and apoptosis. Increases blood-brain barrier permeability and inhibits monoamine oxidase activity in the brain.

Product Specification

Alternative Name:4β,15-Diacetoxy-3α-hydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
 
Formula:C24H34O9
 
MW:466.5
 
Source:Isolated from Fusarium tricinctum.
 
CAS:21259-20-1
 
RTECS:YD0100000
 
Purity:≥98% (TLC)
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in methylene chloride (5mg/ml) or chloroform.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
630-101
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Product Literature References

Mycotoxin occurrence on baled and pit silages collected in Co. Meath: C. McElinney, et al.; Irish J. Agr. Food. Res. 54, 87 (2015), Application(s): Liquid chromatography tandem mass spectrometry for Mycotoxin analysis, Full Text
Cytotoxicity and related effects of T-2 toxin on cultured Vero cells: C. Bouaziz, et al.; Toxicon 48, 343 (2006), Abstract;
Development of apoptosis and changes in lymphocyte subsets in thymus, mesenteric lymph nodes and Peyer’s patches of mice orally inoculated with T-2 toxin: T. Nagata, et al.; Exp. Toxicol. Pathol. 53, 309 (2001), Abstract;
Kinetics of apoptosis-related genes mRNA expression in the dorsal skin of hypotrichotic WBN/ILA-ht rats after topical application of T-2 toxin: S.M. Albarenque, et al.; Exp. Toxicol. Pathol. 52, 553 (2001), Abstract;
Kinetics and distribution of transforming growth factor (TGF)-beta 1 mRNA in the dorsal skin of hypotrichotic WBN/ILA-Ht rats following topical application of T-2 toxin: S.M. Albarenque, et al.; Exp. Toxicol. Pathol. 52, 297 (2000), Abstract;
Thymocyte apoptosis by T-2 toxin in vivo in mice is independent of Fas/Fas ligand system: A.M. Murshedul, et al.; Biosci. Biotechnol. Biochem. 64, 210 (2000), Abstract;
T-2 toxin induces thymic apoptosis in vivo in mice: Z. Islam, et al.; Toxicol. Appl. Pharmacol. 148, 205 (1998), Abstract;
T-2 toxin-induced apoptosis in hematopoietic tissues of mice: J. Shinozuka, et al.; Toxicol. Pathol. 26, 674 (1998), Abstract;
Apoptotic cellular damage in mice after T-2 toxin-induced acute toxicosis: T. Ihara, et al.; Nat. Toxins 5, 141 (1997), Abstract;
T-2 toxin-induced apoptosis in lymphoid organs of mice: J. Shinozuka, et al.; Exp. Toxicol. Pathol. 49, 387 (1997), Abstract;
The structures of toxins from two strains of Fusarium tricinctum: J.R. Bamburg, et al.; Tetrahedron 24, 3329 (1968), Abstract;

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ALX-630-113-M001 1 mg 221.00 USD
 
ALX-630-113-M005 5 mg 858.00 USD
Do you need bulk/larger quantities?
 

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