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Bisbenzimide H33342 . trihydrochloride

DNA dye
 
ALX-620-050-M050 50 mg 40.00 USD
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Cell permeable fluorescent dye that binds to A:T pairs in DNA. Useful for the simultaneous study of the cell cycle and apoptosis in unfixed cells. Also useful for controlling gene expression through binding to RNA aptamers inserted into 5' untranslated region of a messenger RNA. Induces cell differentiation. About 10 times more cell permeable than bisbenzimide H33258 (Prod. No. ENZ-52402). Ex(max): 346nm; Em(max): 460nm.

Product Specification

Alternative Name:HOE 33342, 2'-(4-Ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bis-1H-benzimidazole . 3HCl
 
Formula:C27H28N6O . 3HCl
 
MW:452.6 . 109.4
 
CAS:23491-52-3
 
Purity:≥95% (TLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:Yellow to green powder.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-620-050
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ALX-620-050

Product Literature References

Controlling gene expression in living cells through small molecule-RNA interactions: G. Werstuck & M.R. Green; Science 282, 296 (1998), Abstract;
A flow cytometric method using Hoechst 33342 and propidium iodide for simultaneous cell cycle analysis and apoptosis determination in unfixed cells: F. Belloc, et al.; Cytometry 17, 59 (1994), Abstract;
Spectral studies on 33258 Hoechst and related bisbenzimidazole dyes useful for fluorescent detection of deoxyribonucleic acid synthesis: S.A. Latt & G. Stetten; J. Histochem. Cytochem. 24, 24 (1976), Abstract;

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