NBD FGIN-1-27 Analog

Benzodiazepine receptor ligand



ALX-620-045-MC05	0.5 mg	29.00 USD

ALX-620-045-M001	1 mg	49.00 USD

Fluorescent probe for the peripheral-type benzodiazepine receptor (PBR) (Ex(max): 470nm, Em(max): 530nm). The only available tool for imaging PBRs in cellular systems.

Product Specification

Alternative Name:	N^3'-[6-((7-Nitro-2,1,3-benzoxadiol-4-yl)amino)hexyl]2-phenylindole-3-acetamide

Formula:	C₂₈H₂₈N₆O₄

MW:	512.6

Purity:	≥96%

Appearance:	Red solid.

CAS:	336111-14-9

Solubility:	Soluble in DMSO or 100% ethanol.

Long Term Storage:	+4°C

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Product Literature References

Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis: E.G. Jorda, et al.; Apoptosis 10, 91 (2005), Abstract;

Synthesis and biology of a 7-nitro-2,1,3-benzoxadiazol-4-yl derivative of 2-phenylindole-3-acetamide: a fluorescent probe for the peripheral-type benzodiazepine receptor: A.P. Kozikowski, et al.; J. Med. Chem. 40, 2435 (1997), Abstract;

Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function: V. Papadopoulos; Endocr. Rev. 14, 222 (1993), Abstract;