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Sazetidine-A

Acetylcholine receptor activator
 
ALX-550-520-M001 1 mg 195.00 USD
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Ligand of nicotinic acetylcholine receptors (nAChRs). Potent agonist of native and recombinant α4β2 nACHRs showing differential efficacy on α4β2 nAChRs subtypes.

Product Specification

Formula:C15H20N2O2 . 2HCl
 
MW:260.3 . 73.0
 
CAS:820231-95-6
 
Purity:≥95% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in DMSO, methanol or water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
550-520
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550-520

Product Literature References

Sazetidine-A is a potent and selective agonist at native and recombinant alpha4beta2 nicotinic acetylcholine receptors: R. Zwart, et al.; Mol. Pharmacol. 73, 1838 (2008), Abstract;
Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them: Y. Xiao, et al.; Mol. Pharmacol. 70, 1454 (2006), Abstract; Full Text

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