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MSK-195

TRP channel agonist
 
ALX-550-396-M005 5 mg 310.00 USD
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Potent analgesic with EC50=0.96µg/kg in the acetic acid-induced writhing test. RTX binding affinity (Ki=603nM), agonism (calcium influx; EC50=240nM).

Product Specification

Alternative Name:N-[2-(3,4-Dimethylbenzyl)-3-(pivalyloxy)propyl]-2-[4-(2-aminoethoxy)-3-methoxyphenyl]acetamide
 
Formula:C28H40N2O5
 
MW:484.6
 
CAS:289902-82-5
 
Purity:≥98%
 
Appearance:White solid.
 
Solubility:Soluble in methanol, 100% ethanol, DMSO or other organic solvents; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
550-396
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550-396

Product Literature References

Phenolic modification as an approach to improve the pharmacology of the 3-acyloxy-2-benzylpropyl homovanillic amides and thioureas, a promising class of vanilloid receptor agonists and analgesics: J. Lee, et al.; Bioorg. Med. Chem. 10, 1171 (2002), Abstract;

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