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2-(Phosphonomethyl)-pentanedioic acid

NAALADase inhibitor
 
ALX-550-358-M001 1 mg 62.00 USD
 
ALX-550-358-M005 5 mg 240.00 USD
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Potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase (NAALADase), which is a membrane-bound peptidase that hydrolyses N-acetyl-L-aspartate-L-glutamate (NAAG) (Prod. No. ALX-151-020), a major brain peptide.

Product Specification

Alternative Name:PMPA
 
Formula:C6H11O7P
 
MW:226.1
 
CAS:173039-10-6
 
Purity:≥97% (HPLC)
 
Identity:Determined by NMR.
 
Appearance:Viscous, colorless oil.
 
Solubility:Soluble in water, methanol or DMSO.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-550-358
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ALX-550-358

Product Literature References

Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II: R. Luthi-Carter, et al.; Brain Res. 795, 341 (1998), Abstract;
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase: P.F. Jackson, et al.; J. Med. Chem. 39, 619 (1996), Abstract;

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Glutamate receptor ligand
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ALX-151-020-M010 10 mg 49.00 USD
 
ALX-151-020-M050 50 mg 120.00 USD
Do you need bulk/larger quantities?
 

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