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MDL 105,212 . hydrochloride

Tachykinin antagonist
 
ALX-550-357-M001 1 mg 44.00 USD
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Non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors.

Product Specification

Formula:C34H39Cl2N3O5 . HCl
 
MW:640.6 . 36.5
 
CAS:167261-59-8
 
Purity:≥97% (TLC)
 
Identity:Determined by NMR.
 
Appearance:Off-white solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
ALX-550-357
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ALX-550-357

Product Literature References

Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 279, 732 (1996), Abstract;
Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors: T.P. Burkholder, et al.; Bioorg. Med. Chem. Lett. 6, 951 (1996),
In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 277, 840 (1996), Abstract;

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