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Isovelleral

TRPV1 antagonist
 
ALX-550-356-M001 1 mg 151.00 USD
 
ALX-550-356-M005 5 mg 554.00 USD
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Antagonist with different binding profiles towards the vanilloid receptor 1 (TRPV1).
Activator of TRPA1

Product Specification

Formula:C15H20O2
 
MW:232.3
 
CAS:37841-91-1
 
Purity:≥99%
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in organic solvents.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light.
 
ALX-550-356
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ALX-550-356

Product Literature References

TRPA1 mediates the noxious effects of natural sesquiterpene deterrents: J. Escalera, et al.; J. Biol. Chem. 283, 24136 (2008), Abstract;
Pharmacology of vanilloids at recombinant and endogenous rat vanilloid receptors: V. Ralevic, et al.; Biochem. Pharmacol. 65, 143 (2003), Abstract;
The preparation and bioactivities of (-)-isovelleral: M. Jonassohn, et al.; Bioorg. Med. Chem. 5, 1363 (1997), Abstract;
The stimulation of capsaicin-sensitive neurones in a vanilloid receptor-mediated fashion by pungent terpenoids possessing an unsaturated 1,4-dialdehyde moiety: A. Szallasi, et al.; Br. J. Pharmacol. 119, 283 (1996), Abstract;
Comparison of the antimicrobial and cytotoxic activities of twenty unsaturated sesquiterpene dialdehydes from plants and mushrooms: H. Anke & O. Sterner; Planta Med. 57, 344 (1991), Abstract;
Fungal extractives I. structure of a sesquiterpene dialdehyde from Lactarius by computer simulation of the nmr spectrum: G. Magnusson, et al.; THL 13, 1105 (1972), (Isolation),

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