PPADS . tetrasodium salt

P₂ purinergic receptor antagonist



ALX-550-347-M010	10 mg	26.00 USD

Selective P₂ purinoceptor antagonist which blocks responses at both pre- and postjunctional sites.

Product Specification

Alternative Name:	Pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid . 4Na

Formula:	C₁₄H₁₀N₃O₁₂PS₂ . 4Na

MW:	507.3 . 92.0

Purity:	≥98%

Appearance:	Orange solid.

CAS:	192575-19-2

Solubility:	Soluble in water.

Long Term Storage:	-20°C

Handling:	Protect from light. Hygroscopic.

Please mouse over

Product Literature References

Discrimination by PPADS between endothelial P2Y- and P2U-purinoceptors in the rat isolated mesenteric arterial bed: V. Ralevic & G. Burnstock; Br. J. Pharmacol. 118, 428 (1996), Abstract;

Hydrolysis of P2-purinoceptor agonists by a purified ectonucleotidase from the bovine aorta, the ATP-diphosphohydrolase: M. Picher, et al.; Biochem. Pharmacol. 51, 1453 (1996), Abstract;

PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors: S.J. Charlton, et al.; Br. J. Pharmacol 118, 704 (1996), Abstract;

PPADS: an antagonist at the endothelial P2Y-purinoceptors but not P2U-purinoceptors: C. Brown, et al.; Br. J. Pharmacol. 116, 2413 (1995), Abstract;

Investigation of the actions of PPADS, a novel P2X-purinoceptor antagonist, in the guinea-pig isolated vas deferens: G.J. MacLaren, et al.; Br. J. Pharmacol. 111, 913 (1994), Abstract;

Selective antagonism by PPADS at P2X-purinoreceptors in rabbit isolated blood vessels: A.U. Ziganshin, et al.; Br. J. Pharmacol. 111, 923 (1994), Abstract;

PPADS selectively antagonizes P2X-purinoceptor-mediated responses in the rabbit urinary bladder: A.U. Ziganshin, et al.; Br. J. Pharmacol. 110, 1491 (1993), Abstract;

PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses: G. Lambrecht, et al.; Eur. J. Pharmacol. 217, 217 (1992), Abstract;