Galanthamine . hydrobromide

Acetylcholine esterase inhibitor



ALX-550-336-M050	50 mg	114.00 USD

Replaces Prod. #: BML-C115

Specific, competitive and reversible acetylcholinesterase inhibitor. Alzheimer's disease therapeutic.

Product Specification

Alternative Name:	Galantamine, Nivalin

Formula:	C₁₇H₂₁NO₃ . HBr

MW:	287.4 . 80.9

Purity:	≥98% (HPLC)

Appearance:	White to off-white crystalline solid.

CAS:	1953-04-4

MI:	14: 4340

RTECS:	DF8075000

Solubility:	Soluble in DMSO (10mg/ml) or 100% ethanol (4mg/ml); sparingly soluble in water.

Long Term Storage:	-20°C

Use/Stability:	Solutions are stable for up to 3 months when stored at -20°C.

Hazard:	TOXIC.

Handling:	Protect from moisture.

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Product Literature References

Acetylcholinesterase inhibitors: novel activities of old molecules.: M. Racchi, et al.; Pharmacol. Res. 50, 441 (2004), Abstract;

Galanthamine from snowdrop-the development of a modern drug against Alzheimer's disease from local Caucasian knowledge.: M. Heinrich & H. Lee Teoh; J. Ethnopharmacol 92, 147 (2004), Abstract;

Effects of four non-cholinergic cognitive enhancers in comparison with tacrine and galanthamine on scopolamine-induced amnesia in rats: P. Chopin & M. Briley; Psychopharmacology 106, 26 (1992), Abstract;

Galanthamine treatment in Alzheimer's disease: P. Dal-Bianco, et al.; J. Neural. Transm. Suppl. 33, 59 (1991), Abstract;

Inhibition of acetylcholinesterase activity in human brain tissue and erythrocytes by galanthamine, physostigmine and tacrine: T. Thomsen et al.; Eur. J. Clin. Chem. Clin. Biochem. 29, 487 (1991), Abstract;