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Ruthenium red

Capsaicin and Ca2+ antagonist
ALX-550-295-M500 500 mg 77.00 USD
ALX-550-295-G001 1 g 115.00 USD
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Blocks TRPV1. Capsaicin and calcium antagonist. Inhibitor of Ca2+/Mg2+-ATPase.

Product Specification

Sequence:[(NH3)5RuORu(NH3)4ORu(NH3)5]6+ 6Cl-
Formula:Cl6H42N14O2Ru3 . 4H2O
MW:786.4 . 72.1
MI:14: 8300
Purity:≥90% (metals basis)
Appearance:Dark red to purple crystalline solid.
Solubility:Soluble in water (10mg/ml) or ammonia.
Long Term Storage:Ambient

Product Literature References

Kinesin light chain-4 depletion induces apoptosis of radioresistant cancer cells by mitochondrial dysfunction via calcium ion influx: J.H. Baek, et al.; Cell Death Dis. 9, 496 (2018), Abstract; Full Text
Differential activation and desensitization of sensory neurons by resiniferatoxin: G. Acs, et al.; J. Neurosci. 17, 5622 (1997), Abstract;
Ruthenium red and capsazepine antinociceptive effect in formalin and capsaicin models of pain in mice: A.R. Santos & J.B. Calixto; Neurosci. Lett. 235, 73 (1997), Abstract;
Capsaicin-induced biphasic oxygen uptake in rat muscle: antagonism by capsazepine and ruthenium red provides further evidence for peripheral vanilloid receptor subtypes (VN1/VN2): C.D. Griffiths, et al.; Life Sci. 59, 105 (1996), Abstract;
Inhibition by capsazepine of resiniferatoxin- and capsaicin-induced contractions of guinea pig trachea: J.L. Ellis & B.J. Undem; J. Pharmacol. Exp. Ther. 268, 85 (1994), Abstract;
A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens: C.A. Maggi, et al.; Br. J. Pharmacol. 108, 801 (1993), Abstract;
Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin: S. Bevan, et al.; Br. J. Pharmacol. 107, 544 (1992), Abstract;
Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro: L. Urban and A. Dray; Neurosci. Lett. 134, 9 (1991), Abstract;
Ruthenium red as a capsaicin antagonist: R. Amann & C.A. Maggi; Life Sci. 49, 849 (1991), Abstract;
Capsaicin desensitization in vivo is inhibited by ruthenium red: R. Amann, et al.; Eur. J. Pharmacol. 186, 169 (1990), Abstract;
Effects of ruthenium red on activation of Ca2(+)-dependent cyclic nucleotide phosphodiesterase: H. Masuoka, et al.; BBRC 169, 315 (1990), Abstract;
Interaction of ruthenium red with Ca2(+)-binding proteins: J.H. Charuk, et al.; Anal. Biochem. 188, 123 (1990), Abstract;
The effects of ruthenium red on the response of guinea-pig ileum to capsaicin: L.A. Chahl; Eur. J. Pharmacol. 169, 241 (1989), Abstract;
Differential staining of biological structures by ruthenium red [published erratum appears in J. Microsc. 146, 333 (1987)]: M.G. Gutierrez-Gonzalvez, et al.; J. Microsc. 145, 333 (1987), Abstract;
Ruthenium red as a stain for electron microscopy. Some new aspects of its application and mode of action: R. Dierichs; Histochemistry 64, 171 (1979), Abstract;

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