Selective inhibitor of the Na /H antiporter.
Product Specification
| Alternative Name: | 5-(N-Ethyl-N-isopropyl)amiloride, EIPA |
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| Formula: | C11H18ClN7O |
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| MW: | 299.8 |
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| Purity: | ≥98% |
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| Appearance: | Off-white to yellow solid. |
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| CAS: | 1154-25-2 |
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| Solubility: | Soluble in methanol, DMSO or dilute aqueous acid; insoluble in water. |
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| Long Term Storage: | +4°C |
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| Hazard: | IRRITANT. |
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| Handling: | Protect from light. |
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Product Literature References
Apical membrane Na+/H+ exchange in rat medullary thick ascending limb. pH-dependence and inhibition by hyperosmolality: B.A. Watts III & D.W. Good; J. Biol. Chem.
269, 20250 (1994),
Abstract;
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Regulation of intracellular pH in crypt cells from rabbit distal colon: S.L. Abrahamse, et al.; Am. J. Physiol.
267, G409 (1994),
Abstract;
Influence of atrial natriuretic factor on 5-(N-ethyl-N- isopropyl)amiloride-sensitive 22Na+ uptake in rabbit aorta: S. Gupta, et al.; J. Pharmacol. Exp. Ther.
248, 991 (1989),
Abstract;