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R-(+)-DIOA

K+ channel blocker
 
ALX-550-263-M005 5 mg 143.00 USD
 
ALX-550-263-M025 25 mg 641.00 USD
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Inhibitor of the K+/Cl--cotransport that does not affect the bumetanide-sensitive Na+/K+/Cl--cotransport system.

Product Specification

Alternative Name:R-(+)-Butylindazone, (Dihydroindenyl)oxy alkanoic acid
 
Formula:C20H24Cl2O4
 
MW:399.3
 
CAS:81166-47-4
 
Purity:≥98% (HPLC)
 
Identity:Determined by NMR.
 
Appearance:White solid.
 
Solubility:Soluble in 100% ethanol or dilute aqueous base; insoluble in water or dilute aqueous acid.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
ALX-550-263
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ALX-550-263

Product Literature References

Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl- ]-cotransport system: R.P. Garay, et al.; Mol. Pharmacol. 33, 696 (1988), Abstract;
The significance of the relative effects of loop diuretics and anti-brain edema agents on the Na+,K+,Cl- cotransport system and the Cl-/NaCO3- anion exchanger: R.P. Garay, et al.; Naunyn-Schmiedeberg's Arch. Pharmacol. 334, 202 (1986), Abstract;

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