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Clofilium . tosylate

K+ channel blocker
 
ALX-550-242-M025 25 mg 164.00 USD
 
ALX-550-242-M100 100 mg 678.00 USD
 
ALX-550-242-M250 250 mg 1,676.00 USD
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K+ channel blocker. Antiarrhytmic. Cardiac depressant.

Product Specification

Alternative Name:4-Chloro-N,N-diethyl-N-heptylbenzenebutanaminium . tosylate
 
Formula:C21H37ClN . C7H7O3S
 
MW:339.0 . 171.2
 
CAS:92953-10-1
 
Purity:≥97% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White solid.
 
Solubility:Soluble in water, methanol or DMSO.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
ALX-550-242
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ALX-550-242

Product Literature References

Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis: N. Adragna, et al.; Front. Cell. Neurosci. 9, 255 (2015), Application(s): Cell culture , Abstract;
The differential response of normal and ischaemic Purkinje fibres to clofilium, d-sotalol and bretylium: W.B. Gough & N. el-Sherif; Cardiovasc. Res. 23, 554 (1989), Abstract;
Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked: J.P. Arena & R.S. Kass; Mol. Pharmacol. 34, 60 (1988), Abstract;

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