Bepridil . hydrochloride

Ca²⁺ channel inhibitor



ALX-550-237-M010	10 mg	37.00 USD

ALX-550-237-M025	25 mg	78.00 USD

Non-selective Ca²⁺ channel blocker. Stimulates the binding of 1,4-dihydropyridine-based drugs to Ca²⁺ channels. Inhibits Na⁺/Ca²⁺ exchange.

Product Specification

Alternative Name:	1-Isobutoxy-2-pyrrolidino-3-(N-benzylanilino)propane . HCl

Formula:	C₂₄H₃₄N₂O . HCl

MW:	366.6 . 36.5

Purity:	≥98%

Appearance:	White to off-white solid.

CAS:	74764-40-2

MI:	14: 1150

Solubility:	Soluble in 100% ethanol; insoluble in water.

Long Term Storage:	+20°C

Handling:	Store tightly sealed.

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Product Literature References

Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells: Y.S. Lee, et al.; Cancer Lett. 88, 87 (1995), Abstract;

Bepridil as an antisickling agent: membrane internalization and cell rigidity: R.M. Johnson, et al.; Am. J. Hematol. 46, 310 (1994), Abstract;

Drug action and cellular calcium regulation: R. Janis, et al.; Adv. Drug Res. 16, 309 (1987),

Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes: J.P. Galizzi, et al.; J. Biol. Chem. 261, 1393 (1986), Abstract; Full Text