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Bepridil . hydrochloride

Ca2+ channel inhibitor
 
ALX-550-237-M010 10 mg 42.00 USD
 
ALX-550-237-M025 25 mg 90.00 USD
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Non-selective Ca2+ channel blocker. Stimulates the binding of 1,4-dihydropyridine-based drugs to Ca2+ channels. Inhibits Na+/Ca2+ exchange.

Product Specification

Alternative Name:1-Isobutoxy-2-pyrrolidino-3-(N-benzylanilino)propane . HCl
 
Formula:C24H34N2O . HCl
 
MW:366.6 . 36.5
 
CAS:74764-40-2
 
MI:14: 1150
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in 100% ethanol; insoluble in water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Handling:Store tightly sealed.
 
ALX-550-237
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ALX-550-237

Product Literature References

Intracellular Ca2+ mediates the cytotoxicity induced by bepridil and benzamil in human brain tumor cells: Y.S. Lee, et al.; Cancer Lett. 88, 87 (1995), Abstract;
Bepridil as an antisickling agent: membrane internalization and cell rigidity: R.M. Johnson, et al.; Am. J. Hematol. 46, 310 (1994), Abstract;
Drug action and cellular calcium regulation: R. Janis, et al.; Adv. Drug Res. 16, 309 (1987),
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes: J.P. Galizzi, et al.; J. Biol. Chem. 261, 1393 (1986), Abstract; Full Text

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