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Gallamine triethiodide

Muscarinic acetylcholine receptor M2 antagonist
 
ALX-550-180-M500 500 mg 30.00 USD
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Replaces Prod. #: BML-C112

M2 muscarinic receptor antagonist with pronounced cardioselectivity. Acts via allosteric modulation of preceptor binding.

Product Specification

Formula:C30H60N3O3I3
 
MW:891.5
 
CAS:65-29-2
 
MI:14: 4343
 
RTECS:BS1100000
 
Purity:≥98% (TLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water (25mg/ml) or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Hygroscopic.
 
ALX-550-180
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ALX-550-180

Product Literature References

On the interaction of gallamine with muscarinic receptor subtypes: A.D. Michel et al.; Eur. J. Pharmacol. 182, 335 (1990), Abstract;
Pharmacologic discrimination between receptor heterogeneity and allosteric interaction: resultant analysis of gallamine and pirenzepine antagonism of muscarinic responses in rat trachea: T. Kenakin & C. Boselli ; J. Pharmacol. Exp. Ther. 250, 944 (1989), Abstract;
Binding profile of a novel cardioselective muscarine receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat: R. Hammer et al.; Life Sci. 38, 1653 (1986), Abstract;
Stabilization of antagonist binding to cardiac muscarinic acetylcholine receptors by gallamine and other neuromuscular blocking drugs: J. Nedoma et al.; J. Pharmacol. Exp. Ther. 236, 219 (1986), Abstract;

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