United States
4-Aminopyridine
K+ channel blocker
| ALX-550-141-G005 | 5 g | 13.00 USD |  |
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Induces depolarization of GABA neurons. Non-selective K+ channel blocker. Reverses saxitoxin- and tetrodotoxin-induced cardiorespiratory depression. Increases stimulation-induced release of acetylcholine.
Product Specification
| Alternative Name: | Fampridine, 4-Pyridylamine |
| Identity: | Identity determined by IR. |
| Formula: | C5H6N2 |
| MW: | 94.1 |
| Purity: | ≥98% (TLC; Titration) |
| Appearance: | Off-white to tan solid. |
| CAS: | 504-24-5 |
| MI: | 14: 3933 |
| RTECS: | US1750000 |
| Solubility: | Soluble in water (50mg/ml) or 100% ethanol. |
| Long Term Storage: | +4°C |
| Hazard: | VERY TOXIC. |
| Handling: | Protect from light. |
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Product Literature References
The origin, structure, and pharmacological activity of botulinum toxin: L.L. Simpson; Pharmacol. Rev. 33, 155 (1981), Abstract;
Effects of 4-aminopyridine on normal and demyelinated mammalian nerve fibres: R.M. Sherratt, et al.; Nature 283, 570 (1980), Abstract;
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