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(±)-Huperzine A

Acetylcholine esterase inhibitor
 
ALX-550-064-M005 5 mg 186.00 USD
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Racemic modification of (-)-Huperzine A (Prod. No. ALX-550-065) with acetylcholinesterase inhibitor activity. Has a weaker biological activity than (-)Huperzine A. Neurotoxic.

Product Specification

Alternative Name:(±)-Selagine
 
Formula:C15H18N2O
 
MW:242.3
 
Source:Synthetic.
 
CAS:120786-18-7
 
MI:14: 4755
 
Purity:≥95%
 
Appearance:Off-white solid.
 
Solubility:Soluble in dilute aqueous acids or chloroform.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
ALX-550-064
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ALX-550-064

Product Literature References

Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine: R. Wang, et al.; Acta Pharmacol. Sin. 27, 1 (2006), Abstract;
Huperzine A, a potential therapeutic agent for treatment of Alzheimer’s disease: D.L. Bai, et al.; Curr. Med. Chem. 7, 355 (2000), (Review), Abstract;
Huperzine A ameliorates the spatial working memory impairments induced by AF64A: Q.X. Zhi, et al.; NeuroReport 6, 2221 (1995), Abstract;
An Improved Synthetic Route to Huperzine A; New Analogues and Their Inhibition of Acetylcholinesterase: A.P. Kozikowski, et al.; J. C. S. Chem. Commun. 860 (1993),
Mechanism of inhibition of cholinesterases by huperzine A: Y. Ashani, et al.; BBRC 184, 719 (1992), Abstract;
Potencies and stereoselectivities of enantiomers of huperzine A for inhibition of rat cortical acetylcholinesterase: M. McKinney, et al.; Eur. J. Pharmacol. 203, 303 (1991), Abstract;
Synthesis and Biological Evaluation of (±)-Z-Huperzine A: A.P. Kozikowski, et al.; Tetrahedron Lett. 31, 6159 (1990),
A practical synthesis of the Chinese "nootropic" agent huperzine A: a possible lead in the treatment of Alzheimer's disease: Y. Xia & A.P. Kozikowski; JACS 111, 4116 (1989),
Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat: X.C. Tang, et al.; J. Neurosci. Res. 24, 276 (1989), Abstract;
The effect of the nucleoside transport inhibitor dipyridamole on the incorporation of [3H]thymidine in the rat: J.-S. Liu, et al.; Can. J. Chem. 64, 837 (1986),

Related Products

(-)-Huperzine A 

Acetylcholine esterase inhibitor
102518-79-6, Isolated from Lycopodium sp., ≥95% | Print as PDF
 
ALX-550-065-MC05 0.5 mg 41.00 USD
 
ALX-550-065-M001 1 mg 73.00 USD
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