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L-Quisqualic acid

mGluR and AMPA receptor agonist
 
ALX-550-059-M005 5 mg 110.00 USD
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Replaces Prod. #: BML-EA132

Potent group I mGluR agonist and quis-qualate/AMPA ionotropic receptor agonist. Sensitizes neurons in hippocampus to depo-larization by L-AP6 (“quis” effect).

Product Specification

Formula:C5H7N3O5
 
MW:189.1
 
CAS:52809-07-1
 
MI:14: 8085
 
Purity:≥99% (HPLC)
 
Identity:Determined by 1H-NMR.
 
Appearance:White to off-white powder.
 
Solubility:Soluble in dilute aqueous base.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
550-059
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550-059

Product Literature References

Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology 38, 1431 (1999), (Review), Abstract;
Agonists and antagonists for metabotropic glutamate receptors: P.L. Ornstein, et al.; Curr. Pharm. Design 1, 355 (1995), (Review),
Metabotropic glutamate receptors in brain function and pathology: D.D. Schoepp and P.J. Conn; TIPS 14, 13 (1993), (Review), Abstract;
The action of natural and synthetic isomers of quisqualic acid at a well-defined glutamatergic synapse: P. Boden, et al.; Brain Res. 385, 205 (1986), Abstract;

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