Potent, competitive kainate/quisqualate (non-NMDA) receptor antagonist. For the more soluble form see CNQX . disodium salt (Prod. No. ALX-550-283).
Product Details
| Alternative Name: | 6-Cyano-7-nitroquinoxaline-2,3-dione, FG-9065 |
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| Formula: | C9H4N4O4 |
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| MW: | 232.2 |
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| CAS: | 115066-14-3 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | Off-white to yellow powder. |
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| Solubility: | Soluble in DMSO (10mg/ml) or dilute aqueous base. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Stock solutions are stable for several months when stored at -20°C. |
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| Handling: | Protect from light. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Brainstem metabotropic glutamate receptors reduce food intake and activate dorsal pontine and medullar structures after peripheral bacterial lipopolysaccharide administration: L. Chaskiel, et al.; Neuropharmacology
107, 146 (2016),
Application(s): Cell culture,
Abstract;
Differential effects of the excitatory amino acid antagonists, 6-cyano- 7-nitroquinoxaline-2,3-dione (CNQX) and 3-((+-)-2-carboxypiperazin-4- yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice: L. Turski, et al.; Neurosci. Lett.
113, 66 (1990),
Abstract;
Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists: T. Honoré, et al.; Science,
241, 701 (1988),
Abstract;
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