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L-AP3

mGluR antagonist
 
ALX-550-038-M005 5 mg 38.00 USD
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Selective antagonist of the PI-linked metabotropic glutamate response.

Product Specification

Alternative Name:L(+)-2-Amino-3-phosphonopropanoic acid
 
Formula:C3H8NO5P
 
MW:169.1
 
CAS:23052-80-4
 
Purity:≥97%
 
Appearance:White hygroscopic solid.
 
Solubility:Soluble in water.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light.
 
ALX-550-038
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ALX-550-038

Product Literature References

Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp, et al.; Neuropharmacology 38, 1431 (1999), (Review), Abstract;
Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation: J.J. O'Connor, et al.; Nature 367, 557 (1994), Abstract;
Metabotropic glutamate receptors in brain function and pathology: D.D. Schoepp & P.J. Conn; TIPS 14, 13 (1993), (Review), Abstract;
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons: A.J. Irving, et al.; Eur. J. Pharmacol. 186, 363 (1990), Abstract;
Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid: D.D. Schoepp, et al.; Mol. Pharmacol. 38, 222 (1990), Abstract;

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