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DL-AP3

mGluR antagonist
 
ALX-550-037-M050 50 mg 30.00 USD
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Replaces Prod. #: BML-EA103

Metabotropic glutamate receptor antagonist.

Product Specification

Alternative Name:DL-2-Amino-3-phosphonopropanoic acid
 
Formula:C3H8NO5P
 
MW:169.1
 
CAS:5652-28-8
 
Purity:≥97%
 
Appearance:White powder.
 
Solubility:Soluble in water (25mg/ml).
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light. Hygroscopic.
 
ALX-550-037
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ALX-550-037

Product Literature References

Pharmacological agents acting at subtypes of metabotropic glutamate receptors: D.D. Schoepp; Neuropharmacology 38, 1431 (1999), (Review), Abstract;
The metabotropic glutamate receptor antagonist L-2-amino-3-phosphonopropionic acid inhibits phosphoserine phosphatase: J.E. Hawkinson, et al.; Eur. J. Pharmacol. 307, 219 (1996), Abstract;
1S,3R-ACPD stimulates and L-AP3 blocks Ca2+ mobilization in rat cerebellar neurons: A.J. Irving, et al.; Eur. J. Pharmacol. 186, 363 (1990), Abstract;
Comparison of excitatory amino acid-stimulated phosphoinositide hydrolysis and N-[3H]acetylaspartylglutamate binding in rat brain: selective inhibition of phosphoinositide hydrolysis by 2-amino-3-phosphonopropionate: D.D. Schoepp & B.G. Johnson; J. Neurochem. 53, 273 (1989), Abstract;
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol. 75, 65 (1982), Abstract;

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