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DL-AP5

NMDA receptor antagonist
 
ALX-550-034-M025 25 mg 289.00 USD
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Replaces Prod. #: BML-CA400

Potent and selective NMDA receptor antagonist.

Product Specification

Alternative Name:DL-2-Amino-5-phosphonopentanoic acid, DL-2-Amino-5-phosphonovaleric acid
 
Formula:C5H12NO5P
 
MW:197.1
 
CAS:76326-31-3
 
Purity:≥99% (HPLC, TLC)
 
Appearance:White to off-white powder.
 
Solubility:Soluble in 100mM NaOH or 25mM water.
 
Shipping:Ambient
 
Long Term Storage:Ambient
 
Handling:Protect from light.
 
ALX-550-034
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ALX-550-034

Product Literature References

Structural, conformational, and stereochemical requirements of central excitatory amino acid receptors: J.J. Hansen & P. Krogsgaard-Larsen; Med. Res. Rev. 10, 55 (1990), Abstract;
Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4- phosphonobutyrate in the cat spinal cord: J. Davies and J.C. Watkins; Brain Res. 235, 378 (1982), Abstract;
The effects of a series of omega-phosphonic alpha-carboxylic amino acids on electrically evoked and excitant amino acid-induced responses in isolated spinal cord preparations: R.H. Evans, et al.; Br. J. Pharmacol. 75, 65 (1982), Abstract;
2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation: J. Davies, et al.; Neurosci. Lett. 21, 77 (1981), Abstract;
Excitatory amino acid transmitters: J.C. Watkins and R.H. Evans; Ann. Rev. Pharmacol. Toxicol. 21, 165 (1981), (Review), Abstract;

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