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CTRP5 (mouse), (recombinant)

 
ALX-522-102-C010 10 µg 400.00 USD
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Product Specification

Alternative Name:Complement C1q tumor necrosis factor-related protein 5, C1qTNF5
 
Source:Produced in E. coli. Recombinant mouse CTRP5 (Complement C1q tumor necrosis factor-related protein 5) (aa 16-243) is fused at the N-terminus to a linker peptide (14 aa) and a FLAG®-tag.
 
UniProt ID:Q8K479
 
Concentration:0.1mg/ml after reconstitution.
 
Formulation:Lyophilized. Contains PBS.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:<0.1EU/µg purified protein (LAL test; Bio Whittaker).
 
Reconstitution:Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 
Scientific Background:CTRP5 is a member of the CTRP family designated as C1q tumor necrosis factor-related proteins. The CTRPs are paralogs of the adiponectin protein characterized by an N-terminus variable region and C-terminal globular domain (C1q). CTRP5 is a putative secreted protein. A mutation in CTRP5 gene has been genetically linked to the Late-onset retinal degeneration (L-ORD) disease which leads to severe visual loss.
 
Technical Info/Product Notes:FLAG is a registered trademark of Sigma-Aldrich Co.
 

General Literature References

A family of Acrp30/adiponectin structural and functional paralogs: G.W. Wong, et al.; PNAS 101, 10302 (2004), Abstract;
Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration: C. Hayward, et al.; Hum. Mol. Genet. 12, 2657 (2003), Abstract;

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