CTRP5 (mouse), (recombinant)



ALX-522-102-C010	10 µg	320.00 USD

Product Specification

Alternative Name:	Complement C1q tumor necrosis factor-related protein 5, C1qTNF5

Concentration:	0.1mg/ml after reconstitution.

Endotoxin Content:	<0.1EU/µg purified protein (LAL test; Bio Whittaker).

Purity:	≥95% (SDS-PAGE)

Formulation:	Lyophilized. Contains PBS.

Source/Host:	Produced in E. coli. Recombinant mouse CTRP5 (Complement C1q tumor necrosis factor-related protein 5) (aa 16-243) is fused at the N-terminus to a linker peptide (14 aa) and a FLAG^®-tag.

Reconstitution:	Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.

Long Term Storage:	-20°C

Use/Stability:	Stable for at least 6 months after receipt when stored at -20°C.

Handling:	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Miscellaneous/General:	CTRP5 is a member of the CTRP familly designated as C1q tumor necrosis factor-related proteins. The CTRPs are paralogs of the adiponectin protein caracterized by an N-termius variable region and C-terminal globular domain (C1q). CTRP5 is a putative secreted protein. A mutation in CTRP5 gene has been genetically linked to the Late-onset retinal degeneration (L-ORD) disease wich lead to severe visual loss.

Background / Technical Information:	UniProt ID Q8K479: CTRP5 (mouse)FLAG is a registered trademark of Sigma-Aldrich Co.

General Literature References

A family of Acrp30/adiponectin structural and functional paralogs: G.W. Wong, et al.; PNAS 101, 10302 (2004), Abstract;

Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration: C. Hayward, et al.; Hum. Mol. Genet. 12, 2657 (2003), Abstract;