| ALX-522-076-C010 | 10 µg | 561.00 USD |  |
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| Alternative Name: | CD154, TNFSF 5, gp39 |
| MW: | ~58kDa (SDS-PAGE). |
| Source: | Produced in HEK 293 cells. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to the Fc portion of human IgG1 and a linker peptide (20 aa). |
| UniProt ID: | P29965 |
| Concentration: | 0.1mg/ml after reconstitution. |
| Formulation: | Lyophilized. Contains PBS. |
| Purity: | ≥90% (SDS-PAGE) |
| Endotoxin Content: | <0.1EU/µg purified protein (LAL test; BioWhittaker). |
| Specificity: | Binds to human CD40. |
| Applications: | ELISA, FUNC |
| Application Notes: | ELISA: binds to human CD40:COMP at 2-50 ng/ml. |
| Reconstitution: | Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Use/Stability: | Stable for at least 6 months after receipt when stored at -20°C. |
| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
| Technical Info/Product Notes: | Historical data has shown that Fc (human):CD40L stimulates the proliferation of human dendritic cells. Note: Does not require an enhancer. |
| Regulatory Status: | RUO - Research Use Only |
