Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Toll-like receptor 4 (mouse) (24-334):Fc (human), (recombinant)

 
ALX-522-073-C050 50 µg 393.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:TLR4, CD284
 
MW:~83kDa (SDS-PAGE).
 
Source:Produced in HEK 293 cells. The N-terminal region of the extracellular domain of mouse TLR4 (aa 24-334) is fused at the C-terminus to the Fc portion of human IgG1 and a linker peptide (2 aa).
 
UniProt ID:Q9QUK6, Q8K2T5
 
GenBank ID:AAH29856
 
Concentration:1mg/ml after reconstitution.
 
Formulation:Lyophilized. Contains PBS.
 
Purity:≥90% (SDS-PAGE)
 
Endotoxin Content:<0.1EU/µg purified protein (LAL test; Bio Whittaker).
 
Reconstitution:Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 

Product Literature References

Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy: L. Apetoh, et al.; Nat. Med. 13, 1050 (2007), Abstract;

General Literature References

TLR4 as the mammalian endotoxin sensor: B. Beutler; Curr. Top. Microbiol. Immunol. 270, 109 (2002), (Review), Abstract;
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction: J.C. Chow, et al.; J. Biol. Chem. 274, 10689 (1999), Abstract; Full Text
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene: A. Poltorak, et al.; Science 282, 2085 (1998), Abstract;
Genetic and physical mapping of the Lps locus: identification of the toll-4 receptor as a candidate gene in the critical region: A. Poltorak, et al.; Blood Cells Mol. Dis. 24, 340 (1998), Abstract;

Related Products

Control:Fc fusion protein (human), (recombinant) 

Negative control for Fc chimeric proteins
Produced in HEK 293 cells. The extracellular domain of mutated hThy-1, hThy-1 (RLE) (aa 20-130), is fused to the Fc portion of human IgG1. The integrin binding sequence RLD of hThy-1 has been changed to RLE abolishing the binding of integrins., ≥90% (SDS-PAGE) | Print as PDF
 
ALX-203-004-C050 50 µg 405.00 USD
Do you need bulk/larger quantities?
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
TLR
TLR4
By biological activity:
TLR Recombinant protein
TLR4 Recombinant protein
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Related Literature

Product Flyers
Key TLR Ligands and their Receptors
Key TLR Ligands and their Receptors
Download as PDF

All new literature pieces

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,