Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

CD70 (soluble) (mouse), (recombinant)

 
ALX-522-030-C010 10 µg 393.00 USD
Do you need bulk/larger quantities?
 

Product Specification

Alternative Name:CD27L, TNFSF 7
 
MW:~28kDa (SDS-PAGE).
 
Source:Produced in HEK 293 cells. The extracellular domain of mouse CD70 (CD27L) (aa 52-195) is fused at the N-terminus to a linker peptide (11 aa) and a FLAG®-tag.
 
UniProt ID:O55237
 
Gene/Protein Identifier:A000547 (UCSD Signaling Gateway ID)
 
Concentration:0.1mg/ml after reconstitution.
 
Formulation:Lyophilized. Contains PBS.
 
Purity:≥95% (SDS-PAGE)
 
Endotoxin Content:<0.1EU/µg purified protein (LAL test; Bio Whittaker).
 
Species reactivity:Human, Mouse
 
Specificity:Binds to human and mouse CD27.
 
Applications:ELISA
 
Application Notes:ELISA: binds to CD27 receptor.
Can be used together with anti-FLAG® MAb to detect membrane-bound human and mouse CD27. rmsCD70 saturates its receptor at a concentration range of 0.06-60ng/ml.
 
Reconstitution:Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stable for at least 6 months after receipt when stored at -20°C.
 
Handling:Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
 
Scientific Background:The CD27 ligand (CD27L, CD70) is a member of the tumor necrosis factor (TNF) family. CD27L is a type II, transmembrane protein. Engagement of CD27 by CD27L induces recruitment of TNF receptor-associated factor 2 (TRAF2) and TRAF3. CD27-CD70 interactions have been reported to be involved in several different immune mechanisms such as T, NK and B lymphocytes interactions and costimulation, early thymic differentiation, autoimmune and viral diseases and apoptosis. CD70 is a marker for mature B cells.
 

Product Toolbox

PRODUCT RESOURCES

Datasheet
MSDS
Certificate of Analysis

RELATED PRODUCTS

By target:
CD70
By biological activity:
CD70 Recombinant protein
By catalog section:

PRODUCT SUPPORT

FAQs
Technical Service
Customer Service

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2017 Enzo Life Sciences, Inc.,