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n-Octyl-β-D-thioglucopyranoside

Non-ionic detergent
 
ALX-500-009-G001 1 g 39.00 USD
 
ALX-500-009-G005 5 g 182.00 USD
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OTG is a nonionic detergent that may be used to isolate membrane proteins from E. coli without inactivation. Stable in aqueous solution and easily removed by dialysis.

Product Specification

Alternative Name:n-Octyl-β-D-thioglucoside, OTG
 
Formula:C14H28O5S
 
MW:308.4
 
CAS:85618-21-9
 
Purity:≥98% (HPLC)
 
Identity:Determined by IR.
 
Appearance:White to off-white crystalline powder.
 
Solubility:Soluble in water (8g/100ml) or methanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Protect from light. Hygroscopic.
 
ALX-500-009
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ALX-500-009

Product Literature References

Characterization of mixed non-ionic surfactants n-octyl-beta-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure: C.C. Ruiz & J.A. Molina-Bolivar; J. Colloid. Interface Sci. 361, 178 (2011), Abstract;
Solubilization and structural stability of bacteriorhodopsin with a mild nonionic detergent, n-Octyl-beta-thioglucoside: A. Asada, & M. Sonoyama; Biosci. Biotechnol. Biochem. 75, 376 (2011), Abstract; Full Text
Development and crystallization of a minimal thermostabilised G protein-coupled receptor: T. Warne, et al.; Protein Expr. Purif. 65, 204 (2009), Abstract;
The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state: S. Ravaud, et al.; Biochem. J. 395, 345 (2006), Abstract; Full Text
Use of n-Octyl-β-D-thioglucopyranoside in the isolation of a bacterial membrane protein: an improved method for immunological applications.: J.M. Peula-Garcia, et al.; J. Surface Sci. Technol. 22, 141 (2006), Full Text
Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins: M. Chami, et al.; J. Struct. Biol. 133, 64 (2001), Abstract;
Characteristics of n-octyl beta-D-thioglucopyranoside, a new non-ionic detergent useful for membrane biochemistry: S. Saito & T. Tsuchiya; Biochem. J. 222, 829 (1984), Abstract;
Use of n-octyl-beta-D-thioglucoside, a new nonionic detergent, for solubilization and reconstitution of membrane proteins: T. Tsuchiya & S. Saito; J. Biochem. 96, 1593 (1984), Abstract;

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