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Adenosine 5'-O-(3-thiotriphosphate) . tetralithium salt

K+ channel activator
 
ALX-480-066-M005 5 mg 93.00 USD
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ATP analog that can substitute ATP in various kinase reactions. Substrate and inhibitor of ATP-dependent enzyme systems. The resulting thiophosphorylated proteins are resistant to dephosphorylation by protein phosphatases. Increases the activity of Ca2 -activated K channels.

Product Specification

Alternative Name:ATP-γS . 4Li
 
Formula:C10H12N5O12P3S . 4Li
 
MW:547
 
CAS:93839-89-5
 
Purity:≥90% (HPLC)
 
Appearance:White to off-white solid.
 
Solubility:Soluble in water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Stock solutions may be stored at -80°C for up to 1 month. Product is not sterile.
 
Handling:Protect from moisture.
 
480-066
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480-066

Product Literature References

Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation: J. Chen, et al.; Science 257, 1261 (1992), Abstract;
Regulation of phosphoinositide breakdown by guanine nucleotides: I. Litosch & J.N. Fain; Life Sci. 39, 187 (1986), Abstract;
The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate): S. Chrysogelos, et al.; J. Biol. Chem. 258, 12624 (1983), Abstract; Full Text

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