Adenosine 5'-O-(3-thiotriphosphate) . tetralithium salt

K⁺ channel activator



ALX-480-066-M001	1 mg	24.00 USD

ALX-480-066-M005	5 mg	83.00 USD

ATP analog that can substitute ATP in various kinase reactions. Substrate and inhibitor of ATP-dependent enzyme systems. The resulting thiophosphorylated proteins are resistant to dephosphorylation by protein phosphatases. Increases the activity of Ca²-activated K channels.

Product Specification

Alternative Name:	ATP-γS . 4Li

Formula:	C₁₀H₁₂N₅O₁₂P₃S . 4Li

MW:	520.2 . 27.8

Purity:	≥90%

Appearance:	White to off-white solid.

CAS:	93839-89-5

Solubility:	Soluble in water.

Long Term Storage:	-20°C

Use/Stability:	Stock solutions may be stored at -80°C for up to 1 month. Product is not sterile.

Hazard:	IRRITANT.

Handling:	Protect from moisture.

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Product Literature References

Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation: J. Chen, et al.; Science 257, 1261 (1992), Abstract;

Regulation of phosphoinositide breakdown by guanine nucleotides: I. Litosch & J.N. Fain; Life Sci. 39, 187 (1986), Abstract;

The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate): S. Chrysogelos, et al.; J. Biol. Chem. 258, 12624 (1983), Abstract; Full Text