Theophylline

PDE inhibitor



ALX-480-062-G005	5 g	3.00 USD

ALX-480-062-G025	25 g	10.00 USD

Cyclic phosphodiesterase inhibitor. Weakly inhibits alkaline phosphodiesterases and 5’-nucleotidase. Muscle relaxant, cardiac stimulant and diuretic. Used for the treatment of asthma.

Product Specification

Alternative Name:	1,3-Dimethylxanthine, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione

Formula:	C₇H₈N₄O₂

MW:	180.2

Purity:	≥98%

Appearance:	White solid.

CAS:	58-55-9

MI:	14: 9285

Solubility:	Soluble in dilute aqueous acid, dilute aqueous base or 100% ethanol; insoluble in water.

Long Term Storage:	+20°C

Hazard:	TOXIC.

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Product Literature References

Theophylline: new perspectives for an old drug: P.J. Barnes; Am. J. Respir. Crit. Care Med. 167, 813 (2003), (Review), Abstract;

Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes: R.F. Bruns, et al.; Mol. Pharmacol. 29, 331 (1986), Abstract;

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors: J.W. Daly, et al.; J. Med. Chem. 28, 487 (1985), Abstract;