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NADPH . tetrasodium salt

 
ALX-480-004-M050 50 mg 66.00 USD
 
ALX-480-004-M250 250 mg 219.00 USD
 
ALX-480-004-G001 1 g 701.00 USD
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NADPH provides the reducing equivalents for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of ROS (reactive oxygen species), allowing the regeneration of GSH (reduced glutathione). NADPH is also used for anabolic pathways, such as lipid synthesis, cholesterol synthesis, and fatty acid chain elongation.

The NADPH system is also responsible for generating free radicals in immune cells. These radicals are used to destroy pathogens in a process termed the respiratory burst. It is the source of reducing equivalents for cytochrome P450 hydroxylation of aromatic compounds, steroids, alcohols, and drugs.

Product Specification

Alternative Name:β-Nicotinamide Adenine Dinucleotide Phosphate (reduced form) . 4Na, β-NADPH . 4Na
 
Formula:C21H26N7O17P3 . 4Na
 
MW:741.4 . 92.0
 
CAS:2646-71-1
 
Purity:≥95% (HPLC)
 
Appearance:White to light yellow powder.
 
Solubility:Soluble in water (50mg/ml) or 0.01M sodium hydroxide.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Use/Stability:NADPH is unstable in acid media. Stock solutions should be at pH 8.
 
Handling:Protect from light.
 
ALX-480-004
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ALX-480-004

Product Literature References

Globular adiponectin attenuates LPS-induced reactive oxygen species production in HepG2 cells via FoxO3A and HO-1 signaling: A. Shrestha & P.H. Park; Life Sci. 148, 71 (2016), Application(s): Cell culture, Abstract;
Tales of Dihydrofolate Binding to R67 Dihydrofolate Reductase: M.R. Duff, et al.; Biochemistry 55, 133 (2016), Abstract; Full Text
Efferent and afferent innervation of primate trabecular meshwork and scleral spur: J.M. Selbach, et al.; Invest. Ophthalmol. Vis. Sci. 41, 2184 (2000), Abstract; Full Text

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