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Necrostatin-7

Necroptosis inhibitor
 
ALX-430-170-M005 5 mg 93.00 USD
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Necroptosis inhibitor. The biological activity of necrostatin-7 (Nec-7) is different from that of necrostatin-1 to -5 (Nec-1 to -5), as Nec-7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.

Product Specification

Formula:C16H10N5OS2F
 
MW:371.4
 
CAS:351062-08-3
 
Purity:≥98% (HPLC, TLC)
 
Appearance:Yellow solid.
 
Solubility:Soluble in DMSO or 100% ethanol.
 
Shipping:Ambient
 
Long Term Storage:-20°C
 
Handling:Keep cool and dry. Packaged under inert gas.
 
430-170
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Product Literature References

Retinal pigment epithelial cell necroptosis in response to sodium iodate: J. Hanus, et al.; Cell Death Discov. 2, Article number 16054 (2016), Application(s): Cell culture, transfection, treatments, and MTT assay (human cells), Full Text
Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7: W. Zheng, et al.; Bioorg. Med. Chem. Lett. 18, 4932 (2008), Abstract;

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Necrostatin-1 

Inhibits necroptosis
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