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5-Aminosalicylic acid

NF-κB pathway inhibitor
 
ALX-430-110-G005 5 g 34.00 USD
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Inhibits TNF-α regulated IκB degradation and NF-κB activation.

Product Specification

Alternative Name:5-ASA, Mesalamine, 5-Amino-2-hydroxybenzoic acid
 
Formula:C7H7NO3
 
MW:153.1
 
CAS:89-57-6
 
MI:14: 5904
 
Purity:≥98% (Assay)
 
Identity:Determined by IR.
 
Appearance:White to light gray or light pink powder or crystalline solid.
 
Solubility:Soluble in 1 M hydrochloric acid.
 
Shipping:Ambient
 
Long Term Storage:+4°C
 
Handling:Protect from light.
 
430-110
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430-110

Product Literature References

Aminosalicylic acid inhibits IkappaB kinase alpha phosphorylation of IkappaBalpha in mouse intestinal epithelial cells: F. Yan & D.B. Polk; J. Biol. Chem. 274, 36631 (1999), Abstract; Full Text
Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine: S. Liptay, et al.; Br. J. Pharmacol. 128, 1361 (1999), Abstract;

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