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DPTA NONOate

Nitric oxide donor
 
ALX-430-066-M005 5 mg 36.00 USD
 
ALX-430-066-M025 25 mg 114.00 USD
 
ALX-430-066-5005 5x5 mg 149.00 USD
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Nitric oxide (NO) donor. The half-life time is 5 hours at 22°C in 0.1M phosphate buffer, pH 7.4. Decomposition of NONOates is nearly instantaneous at pH 5.0.

Product Specification

Alternative Name:Dipropylenetriamine NONOate
 
Formula:C6H17N5O2
 
MW:191.2
 
CAS:146724-95-0
 
Purity:≥98% (NMR)
 
Appearance:White to off-white solid.
 
Solubility:Highly soluble in water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-80°C
 
Handling:Protect from light and moisture. Aqueous solutions should be prepared fresh daily.
 
ALX-430-066
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ALX-430-066

Product Literature References

Control of disease tolerance to malaria by nitric oxide and carbon monoxide: V. Jeney, et al.; Cell Rep. 8, 126 (2014), Application(s): Injection of DPTA-NO and assessment with NO Detection Kit, cGMP Enzyme EIA, Abstract;
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation. A novel antiapoptotic mechanism that suppresses apoptosis: N. Azad, et al.; J. Biol. Chem. 281, 34124 (2006), Abstract;
In vitro cytotoxicity of glyco-S-nitrosothiols. a novel class of nitric oxide donors: H. Babich & H.L. Zuckerbraun; Toxicol. In Vitro 15, 181 (2001), Abstract;
In vitro cytotoxicity of the nitric oxide donor, S-nitroso-N-acetyl-penicillamine, towards cells from human oral tissue: H. Babich, et al.; Pharmacol. Toxicol. 84, 218 (1999), Abstract;
New Nitric Oxide-Releasing Zwitterions Derived from Polyamines: J.A. Hrabie, et al.; J. Org. Chem. 58, 1472 (1993),

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