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MAHMA NONOate

Nitric oxide donor
 
ALX-430-015-M005 5 mg 34.00 USD
 
ALX-430-015-M025 25 mg 116.00 USD
 
ALX-430-015-5005 5x5 mg 138.00 USD
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Nitric oxide (NO) donor. The half-life time of MAHMA NONOate is 2.7 min. at 22°C in 0.1M phosphate buffer, pH 7.4. Decomposition of NONOates is nearly instantaneous at pH 5.0.

Product Specification

Alternative Name:NOC-9, MAHMA/NO, (Z)-1-(N-Methyl-N-[6-(N-methylammoniohexyl)amino])-diazen-1-ium-1,2-diolate
 
Formula:C8H20N4O2
 
MW:204.3
 
CAS:146724-86-9
 
Purity:≥98%
 
Appearance:White to off-white crystalline solid.
 
Solubility:Soluble in water.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Relatively stable in alkaline solution.
 
Handling:Protect from light and moisture.
 
ALX-430-015 structure
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ALX-430-015 structure

Product Literature References

Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT): L.J. Bryan-Lluka, et al.; Br. J. Pharmacol. 143, 63 (2004), Abstract;
Platelet inhibitory effects of the nitric oxide donor drug MAHMA NONOate in vivo in rats: K.L. Homer & J.C. Wanstall; Eur. J. Pharmacol. 482, 265 (2003), Abstract;
Inhibition of rat platelet aggregation by the diazeniumdiolate nitric oxide donor MAHMA NONOate: K.L. Homer & J.C. Wanstall; Br. J. Pharmacol. 137, 1071 (2002), Abstract;
New nitric oxide-releasing zwitterions derived from polyamines: J.A. Hrabie, et al.; J. Org. Chem. 58, 1472 (1993),

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