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NOR-4

Nitric oxide donor
 
ALX-430-012-M005 5 mg 69.00 USD
 
ALX-430-012-M010 10 mg 134.00 USD
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Nitric oxide (NO) donor.

Product Specification

Alternative Name:FR 144420, (±)-(E)-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenecarbamoylpyridine
 
Formula:C14H18N4O4
 
MW:306.3
 
CAS:162626-99-5
 
Purity:≥97% (HPLC)
 
Appearance:White to off-white crystalline powder.
 
Solubility:Soluble in DMSO (10mg/ml).
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Use/Stability:Half life time in aqueous solution, pH 7.4, is t½ = 60 minutes.
 
Handling:Protect from light and moisture. Packaged under inert gas.
 
ALX-430-012
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ALX-430-012

Product Literature References

Differences in neuritogenic response to nitric oxide in PC12 and PC12h cells: M. Yamazaki, et al.; Neurosci. Lett. 393, 222 (2006), Abstract;
Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19: D. Giordano, et al.; Blood 107, 1537 (2006), Abstract;
Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of NO release: T. Yamamoto, et al.; Eur. J. Pharmacol. 397, 25 (2000), Abstract;
Antianginal effects of FR144420, a novel slow nitric oxide-releasing agent: Y. Hirasawa, et al.; Eur. J. Pharmacol. 303, 55 (1996), Abstract;
Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners: Y. Kita, et al.; J. Pharmacol. Exp. Ther. 276, 421 (1996), Abstract;
FR144420, a novel, slow, nitric oxide-releasing agent: Y. Kita, et al.; Eur. J. Pharmacol. 275, 125 (1995), Abstract;

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